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Article

CREB Binds to Multiple Loci on Human Chromosome 22

13 Apr 2004

Abstract excerpt

The cyclic AMP-responsive element-binding protein (CREB) is an important transcription factor that can be activated by hormonal stimulation and regulates neuronal function and development. An unbiased, global analysis of where CREB binds has not been performed. We have mapped for the first time the binding distribution of CREB along an entire human chromosome. Chromatin immunoprecipitation of CREB-associated DNA...

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Identifiers

PMID: 15082775
DOI: 10.1128/mcb.24.9.3804-3814.2004

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