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Article

PKA/CREB regulates the constitutive promoter activity of the USP22 gene.

Oncology reports - 1 Mar 2015

Xiong Jianjun, Zhou Xiaoou, Gong Zhen, Wang Ting, Zhang Chao, Xu Xiaoyuan, Liu Jianyun, Li Weidong

Abstract excerpt

The human ubiquitin-specific processing enzyme 22 (USP22) plays a crucial role in regulating cell cycle processes and its overexpression has been linked to tumor progression. However, the mechanisms leading to USP22 transcriptional activation in human cancer cells are still unclear. Previously, we characterized the 5'-flanking sequence of the human USP22 gene and found a potential CREB/ATF binding site within the...

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Identifiers

PMID: 25607216
DOI: 10.3892/or.2015.3740

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USP22

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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