Article
Posttranscriptional regulation of HO expression by the Mkt1-Pbp1 complex.
Molecular and cellular biology - 1 May 2004
Tadauchi Tomofumi, Inada Toshifumi, Matsumoto Kunihiro, Irie Kenji
Abstract excerpt
Cells of budding yeast give rise to mother and daughter cells, which differ in that only mother cells express the HO endonuclease gene and are thereby able to switch mating types. In this study, we identified the MKT1 gene as a positive regulator of HO expression. The MKT1 gene encodes a protein with two domains, XPG-N and XPG-I, which are conserved among a family of nucleases, including human XPG endonuclease....
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