Article
Both HMG boxes in Hmo1 are essential for DNA binding in vitro and in vivo.
Bioscience, biotechnology, and biochemistry - 1 Jan 2015
Higashino Ayako, Shiwa Yuh, Yoshikawa Hirofumi, Kokubo Tetsuro, Kasahara Koji
Abstract excerpt
Hmo1, a member of the high mobility group B family proteins in Saccharomyces cerevisiae, associates with the promoters of ribosomal protein genes (RPGs) to direct accurate transcriptional initiation. Here, to identify factors involved in the binding of Hmo1 to its targets and the mechanism of Hmo1-dependent transcriptional initiation, we developed a novel reporter system using the promoter of the RPG RPS5. A...
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