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Article

Cryptococcus neoformans CAP59 (or Cap59p) is involved in the extracellular trafficking of capsular glucuronoxylomannan.

Eukaryotic cell - 1 Apr 2004

García-Rivera Javier, Chang Yun C, Kwon-Chung K J, Casadevall Arturo

Abstract excerpt

Several genes are essential for Cryptococcus neoformans capsule synthesis, but their functions are unknown. We examined the localization of glucuronoxylomannan (GXM) in strain B-3501 and in cap59 mutants B-4131 and C536. Wild-type strain B-3501 showed a visible capsule by India ink staining and immunofluorescence with anticapsular monoclonal antibodies (MAbs) 12A1 and 18B7. B-4131, a mutant containing a missense...

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Identifiers

PMID: 15075268
DOI: 10.1128/EC.3.2.385-392.2004
PMCID: PMC387637

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Source receipt: pubmed, retrieved 7 Sept 2026.

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