Article
Cas3p belongs to a seven-member family of capsule structure designer proteins.
Eukaryotic cell - 1 Dec 2004
Moyrand Frédérique, Chang Yun C, Himmelreich Uwe, Kwon-Chung Kyung J, Janbon Guilhem
Abstract excerpt
The polysaccharide capsule is the main virulence factor of the basidiomycetous yeast Cryptococcus neoformans. Four genes (CAP10, CAP59, CAP60, and CAP64) essential for capsule formation have been previously identified, although their roles in the biosynthetic pathway remain unclear. A genetic and bioinformatics approach allowed the identification of six CAP64-homologous genes, named CAS3, CAS31, CAS32, CAS33,...
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