Article
Isolation, Characterization, and Localization of a Capsule-Associated Gene, CAP10 , of Cryptococcus neoformans
15 Sept 1999
Abstract excerpt
Cryptococcus neoformans is a pathogenic fungus which most commonly affects the central nervous system and causes fatal meningoencephalitis primarily in patients with AIDS. This fungus produces a thick extracellular polysaccharide capsule which is well recognized as a virulence factor. Here, we describe the isolation and characterization of a novel gene, CAP10, which is required for capsule formation....
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