Article
Conformational variation between allelic variants of cell-surface ovine prion protein.
The Biochemical journal - 1 Jul 2004
Thackray Alana M, Yang Sujeong, Wong Edmond, Fitzmaurice Tim J, Morgan-Warren Robert J, Bujdoso Raymond
Abstract excerpt
The distribution of prion infectivity and PrPSc between peripheral lymphoid tissues suggests their possible haematogenic spread during the progression of natural scrapie in susceptible sheep. Since ovine PBMCs (peripheral blood mononuclear cells) express PrPC, they have the potential to carry or...
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