Article
Genomewide linkage analysis of bipolar disorder by use of a high-density single-nucleotide-polymorphism (SNP) genotyping assay: a comparison with microsatellite marker assays and finding of significant linkage to chromosome 6q22.
American journal of human genetics - 1 May 2004
Middleton F A, Pato M T, Gentile K L, Morley C P, Zhao X, Eisener A F, Brown A, Petryshen T L, Kirby A N, Medeiros H, Carvalho C, Macedo A, Dourado A, Coelho I, Valente J, Soares M J, Ferreira C P, Lei M, Azevedo M H, Kennedy J L, Daly M J, Sklar P, Pato C N
Abstract excerpt
We performed a linkage analysis on 25 extended multiplex Portuguese families segregating for bipolar disorder, by use of a high-density single-nucleotide-polymorphism (SNP) genotyping assay, the GeneChip Human Mapping 10K Array (HMA10K). Of these families, 12 were used for a direct comparison of...
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