Article
SNP fine mapping of chromosome 8q24 in bipolar disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2007
Zandi Peter P, Avramopoulos Dimitrios, Willour Virginia L, Huo Yuqing, Miao Kuangyi, Mackinnon Dean F, McInnis Melvin G, Potash James B, Depaulo J Raymond
Abstract excerpt
We previously reported linkage to chromosome 8q24 in bipolar disorder (BP) with a LOD of 3.32. We fine mapped the locus with SNPs and tested for association with BP in families with evidence of linkage to the region. We genotyped 249 informative SNPs over 3.4 Mb in an initial sample of 155 nuclear families (352 affected offsprings), and followed up the best findings by genotyping six of the most significantly...
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