Article
Increasing incidence of Type 1 diabetes--role for genes?
BMC genetics - 2 Apr 2004
Pitkäniemi Janne, Onkamo Päivi, Tuomilehto Jaakko, Arjas Elja
Abstract excerpt
BACKGROUND: The incidence of Type 1 diabetes (T1DM) is increasing fast in many populations. The reasons for this are not known, although an increase in the penetrance of the diabetes-associated alleles, through changes in the environment, might be the most plausible mechanism. After the introduction of insulin treatment in 1930s, an increase in the pool of genetically susceptible individuals has been suggested to...
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