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Article

Estimation of genetic risk for type 1 diabetes.

American journal of medical genetics - 30 May 2002

Ilonen Jorma, Sjöroos Minna, Knip Mikael, Veijola Riitta, Simell Olli, Akerblom Hans K, Paschou Peri, Bozas Evangelos, Havarani Beatrice, Malamitsi-Puchner Ariadne, Thymelli Joanna, Vazeou Andriani, Bartsocas Christos S

Abstract excerpt

The most important gene loci defining risk of type 1 diabetes mellitus (T1DM) are located within the HLA gene region. HLA-DQ molecules are of primary importance but HLA-DR gene products modify the risk conferred by HLA-DQ. The risk associated with an HLA genotype is defined by the particular combination of susceptible and protective alleles. The highest risk is associated with a combination of two different risk...

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Share to Diabetes and associated disorders
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Histocompatibility Testing

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Source

Identifiers

PMID: 12116174
DOI: 10.1002/ajmg.10341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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