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Article

The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes.

Lancet (London, England) - 1 Jan 2000

Gillespie Kathleen M, Bain Steven C, Barnett Anthony H, Bingley Polly J, Christie Michael R, Gill Geoffrey V, Gale Edwin A M

Abstract excerpt

The incidence of childhood type 1 diabetes has risen over the past 50 years. We compared the frequency of HLA class II haplotypes in 194 patients diagnosed more than 50 years ago and 582 age-matched and sex-matched individuals diagnosed between 1985 and 2002. The proportion of high-risk susceptib...

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Identifiers

PMID: 15530631
DOI: 10.1016/S0140-6736(04)17357-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15530631-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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