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Article

Increased risk of type 1 diabetes in Polish children - association with INS-IGF2 5'VNTR and lack of association with HLA haplotype.

Endokrynologia Polska - 1 Jan 2011

Fendler Wojciech, Klich Izabela, Cieślik-Heinrich Agnieszka, Wyka Krystyna, Szadkowska Agnieszka, Młynarski Wojciech

Abstract excerpt

BACKGROUND: Human leukocyte antigens (HLA) complex and INS-IGF2 5'VNTR loci are principal determinants of the risk of type 1 diabetes mellitus (T1DM). Carriage of class III allele is protective, while class I/I homozygosity increases the risk of T1DM. MATERIAL AND METHODS: HLA and 5'VNTR allele frequencies were summarised and multivariate logistic regression models with interaction evaluation were employed to...

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Identifiers

PMID: 22069105

Genes

IGF2
INS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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