Article
HLA alleles and type 1 diabetes mellitus in low disease incidence populations of Southern Europe: a comparison of Greeks and Albanians.
Journal of pediatric endocrinology & metabolism : JPEM - 1 Feb 2004
Paschou Peristera, Bozas Evangelos, Dokopoulou Maria, Havarani Beatrice, Malamitsi-Puchner Ariadne, Ylli Agron, Ylli Zamira, Thymelli Ioanna, Gerasimidi-Vazeou Andriani, Bartsocas Christos S
Abstract excerpt
Type 1 diabetes mellitus (DM1) is caused by environmental factors acting on genetically susceptible individuals. HLA-DQA1 and -DQB1 are major genetic determinants of the disease. Greece and Albania represent the low DM1 incidence countries of South-Eastern Europe. The HLA-DQA1 and -DQB1 associations with DM1 were investigated in these two groups, as reference for comparisons to the high-risk populations of...
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