Article
HLA-associated genetic resistance and susceptibility to type I diabetes in French North Africans and French natives.
Tissue antigens - 1 Sept 2007
Guérin V, Léniaud L, Pédron B, Guilmin-Crépon S, Tubiana-Rufi N, Sterkers G
Abstract excerpt
The distribution of human leukocyte antigen (HLA)-DRB1-DQA1-DQB1 haplotypes was analyzed separately in two distinct French ethnic groups with type I diabetes (T1D), i.e. French North African migrants (n= 64, mean age at diagnosis = 8.25 years) and ancient French natives (n= 60, mean age at diagnosis = 7.42 years). HLA associations were determined by calculating odds ratios (ORs) between patients and two...
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