Article
Cell-division-cycle defects associated with fission yeast pre-mRNA splicing mutants.
Current genetics - 1 Sept 1998
Potashkin J, Kim D, Fons M, Humphrey T, Frendewey D
Abstract excerpt
We have isolated six new pre-mRNA splicing mutants (prp) from a collection of temperature-sensitive (ts-) Schizosaccharomyces pombe strains. The prp mutants are defective in the splicing of both messenger RNA and U6 small nuclear RNA precursors. A single recessive mutation is responsible for both the ts- growth and the splicing phenotypes in each of the prp mutants. The six prp mutations are unlinked and fall...
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