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Article

Isolation of an essential Schizosaccharomyces pombe gene, prp31(+), that links splicing and meiosis.

Nucleic acids research - 1 Jun 2000

Bishop D T, McDonald W H, Gould K L, Forsburg S L

Abstract excerpt

We carried out a screen for mutants that arrest prior to premeiotic S phase. One of the strains we isolated contains a temperature-sensitive allele mutation in the fission yeast prp31(+) gene. The prp31-E1 mutant is defective in vegetative cell growth and in meiotic progression. It is synthetically lethal with prp6 and displays a pre-mRNA splicing defect at the restrictive temperature. We cloned the wild-type...

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Identifiers

PMID: 10871341
DOI: 10.1093/nar/28.11.2214
PMCID: PMC102626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Isolation of an essential Schizosaccharomyces pombe gene, prp31(+), that links splicing and meiosis.PMID 10871341Read ↗

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