Article
Imaging of bioluminescent LNCaP-luc-M6 tumors: a new animal model for the study of metastatic human prostate cancer.
The Prostate - 15 May 2004
Scatena Caroline D, Hepner Mischa A, Oei Yoko A, Dusich Joan M, Yu Shang-Fan, Purchio Tony, Contag Pamela R, Jenkins Darlene E
Abstract excerpt
BACKGROUND: Animal experiments examining hormone-sensitive metastatic prostate cancer using the human LNCaP cell line have been limited to endpoint analyses. To permit longitudinal studies, we generated a luciferase-expressing cell line and used bioluminescent imaging (BLI) to non-invasively monitor the in vivo growth of primary LNCaP tumors and metastasis. METHODS: LNCaP.FGC cells were transfected to...
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