Article
Brief report: a bioassay to identify primary human prostate cancer repopulating cells.
Stem cells (Dayton, Ohio) - 1 Aug 2011
Toivanen Roxanne, Berman David M, Wang Hong, Pedersen John, Frydenberg Mark, Meeker Alan K, Ellem Stuart J, Risbridger Gail P, Taylor Renea A
Abstract excerpt
Cancer cells are heterogeneous in both their phenotypes and ability to promote tumor growth and spread. Xenografting is used to identify the most highly capable cells of regenerating tumors, referred to as cancer repopulating cells. Because prostate cancers (PCa's) rarely grow as xenografts, inde...
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