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Article

Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 1996

Pettaway C A, Pathak S, Greene G, Ramirez E, Wilson M R, Killion J J, Fidler I J

Abstract excerpt

The purpose of this study was to determine whether the implantation of human prostate cancer cells into the prostates of nude mice and their subsequent growth there can be used to select variants with increasing metastatic potential. PC-3M and LNCaP cells were injected into the prostates of athymic mice. Tumors from the prostate or lymph nodes were harvested, and cells were reinjected into the prostate. This...

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PMID: 9816342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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