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Article

S-palmitoylation modulates human estrogen receptor-alpha functions.

Biochemical and biophysical research communications - 9 Apr 2004

Acconcia Filippo, Ascenzi Paolo, Fabozzi Giulia, Visca Paolo, Marino Maria

Abstract excerpt

17beta-Estradiol (E2)-induced rapid functions (from seconds to minutes) can be attributed to a fraction of nuclear estrogen receptor-alpha (ERalpha) localized at the plasma membrane. As a potential mechanism, we postulated that S-palmitoylation of the Cys447 residue may explain the ability of ERalpha to associate to plasma membrane making possible E2-dependent rapid functions [e.g., extracellular regulated kinase...

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Identifiers

PMID: 15033483
DOI: 10.1016/j.bbrc.2004.02.129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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