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Article

Palmitoylation of estrogen receptors is essential for neuronal membrane signaling.

Endocrinology - 1 Nov 2013

Meitzen John, Luoma Jessie I, Boulware Marissa I, Hedges Valerie L, Peterson Brittni M, Tuomela Krista, Britson Kyla A, Mermelstein Paul G

Abstract excerpt

In addition to activating nuclear estrogen receptor signaling, 17β-estradiol can also regulate neuronal function via surface membrane receptors. In various brain regions, these actions are mediated by the direct association of estrogen receptors (ERs) activating metabotropic glutamate receptors (mGluRs). These ER/mGluR signaling partners are organized into discrete functional microdomains via caveolin proteins. A...

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Identifiers

PMID: 24008343
DOI: 10.1210/en.2013-1172
PMCID: PMC3800757

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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