Article
Transcriptional regulation of IER5 in response to radiation in HepG2.
Cancer gene therapy - 1 Jan 2000
Yang C, Yin L, Zhou P, Liu X, Yang M, Yang F, Jiang H, Ding K
Abstract excerpt
Radiotherapy is one of the important treatments for patients with hepatocellular carcinoma. The treatment response (or efficacy), however, is limited in many patients due to acquired radiation resistance of cancer cells. Immediate-early response 5 (IER5) is one of the genes upregulated on radiation. The gene could modulate cell cycle checkpoint, leading to a decrease of cancer cell survival in response to...
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