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Growth arrest and DNA damage-inducible 45: a new player on inflammatory diseases

27 Feb 2025

Abstract excerpt

Growth arrest and DNA damage-inducible 45 (GADD45) proteins are critical stress sensors rapidly induced in response to genotoxic/physiological stress and regulate many cellular functions. Even though the primary function of the proteins is to block the cell cycle, inhibit cell proliferation, promote cell apoptosis, and repair DNA damage to cope with the damage caused by internal and external stress on the body,...

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PMID: 40083548
DOI: 10.3389/fimmu.2025.1513069

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