Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic stability of mature dendritic cells tuned by TLR or CD40 to control the efficiency of cytotoxic T cell priming.

Microbiology and immunology - 1 Jan 2004

Nakamura Ichiro, Kajino Kiichi, Bamba Hiromichi, Itoh Fumito, Takikita Mikiko, Ogasawara Kazumasa

Abstract excerpt

It is generally accepted that after stimulation immature DCs turn into mature DCs, which present exogenous antigens together with their MHC class I molecules and then activate the antigen-specific CTLs. Although both TLR and CD40 stimulation appeared to provide the same effects on DC maturation, CD40-dependent CTL activation is much more potent than CTL activation through LPS stimulation. Despite their different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD40 Antigens
Share to Dendritic Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

Share to Phenotype

Share to Spleen

Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 15031535
DOI: 10.1111/j.1348-0421.2004.tb03508.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic stability of mature dendritic cells tuned by TLR or CD40 to control the efficiency of cytotoxic T cell priming.PMID 15031535Read ↗

Maturation induction of human peripheral blood mononuclear cell-derived dendritic cellsSemantic proximity Read ↗

Interferon gamma stimulates cellular maturation of dendritic cell line DC2.4 leading to induction of efficient cytotoxic T cell responses and antitumor immunity.Semantic proximity Read ↗

Depending on their maturation state, splenic dendritic cells induce the differentiation of CD4(+) T lymphocytes into memory and/or effector cells in vivo.Semantic proximity Read ↗

Dendritic cells as gatekeepers of tolerance.Semantic proximity Read ↗

Alternatively activated dendritic cells derived from systemic lupus erythematosus patients have tolerogenic phenotype and function.Semantic proximity Read ↗

Type I IFN drives a distinctive dendritic cell maturation phenotype that allows continued class II MHC synthesis and antigen processing.Semantic proximity Read ↗

Dynamic changes of phenotypes and secretory functions during the differentiation of pre-DCs to mature DCs.Semantic proximity Read ↗

Epigenetic stabilization of DC and DC precursor classical activation by TNFα contributes to protective T cell polarization.Semantic proximity Read ↗

Comparison of morphology, phenotypes and function between cultured human IL‑4‑DC and IFN‑DC.Semantic proximity Read ↗

Short-term activation induces multifunctional dendritic cells that generate potent antitumor T-cell responses in vivo.Semantic proximity Read ↗

LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells.Semantic proximity Read ↗

Intermediate maturation of Mycobacterium tuberculosis LAM-activated human dendritic cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.