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Article

Limited role of the Toll-like receptor-2 in resistance to Mycobacterium avium.

Immunology - 1 Feb 2004

Gomes M Salomé, Flórido Manuela, Cordeiro João V, Teixeira C Miguel, Takeuchi Osamu, Akira Shizuo, Appelberg Rui

Abstract excerpt

The role of the Toll-like receptor (TLR)-2 in the generation of protective immunity to Mycobacterium avium was evaluated using gene-disrupted mice. TLR-2-/- mice were more susceptible than wild-type C57Bl/6 mice to M. avium strains that were able to proliferate in vivo before the development of protective immunity and mycobacteriostasis. In contrast, the elimination of non-virulent strains was not affected by the...

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Identifiers

PMID: 15027903
DOI: 10.1111/j.0019-2805.2003.01807.x
PMCID: PMC1782404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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