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Article

Dual role of TLR2 and myeloid differentiation factor 88 in a mouse model of invasive group B streptococcal disease.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2004

Mancuso Giuseppe, Midiri Angelina, Beninati Concetta, Biondo Carmelo, Galbo Roberta, Akira Shizuo, Henneke Philipp, Golenbock Douglas, Teti Giuseppe

Abstract excerpt

Toll-like receptors (TLRs) are involved in pathogen recognition by the innate immune system. Different TLRs and the adaptor molecule myeloid differentiation factor 88 (MyD88) were previously shown to mediate in vitro cell activation induced by group B streptococcus (GBS). The present study examined the potential in vivo roles of TLR2 and MyD88 during infection with GBS. When pups were infected locally with a low...

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Share to Antigens, Differentiation
Share to Dose-Response Relationship, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Streptococcus agalactiae

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Source

Identifiers

PMID: 15128822
DOI: 10.4049/jimmunol.172.10.6324

Genes

TLR2
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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