Article
Higher maturity and connective tissue association distinguish resident from recently generated human tonsil plasma cells.
Journal of leukocyte biology - 1 Dec 2007
Medina Francisco, Segundo Carmen, Jiménez-Gómez Gema, González-García Inés, Campos-Caro Antonio, Brieva José A
Abstract excerpt
Human plasma cells (PC) are present in cell suspensions obtained from the tonsil by mechanical disaggregation (PC(MECH)). The present study shows that a collagenase treatment of tonsillar debris remaining after mechanical disaggregation yielded similar proportions of PC (PC(COLL)). Moreover, PC(MECH) were present in suspensions highly enriched in germinal center cells whereas PC(COLL) contained most of the...
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