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Article

Phototransduction in Drosophila Is Compromised by Gal4 Expression but not by InsP3 Receptor Knockdown or Mutation.

eNeuro - 1 Jan 2000

Bollepalli Murali K, Kuipers Marije E, Liu Che-Hsiung, Asteriti Sabrina, Hardie Roger C

Abstract excerpt

Drosophila phototransduction is mediated by phospholipase C, leading to activation of transient receptor potential (TRP) and TRP-like (TRPL) channels by mechanisms that are unresolved. A role for InsP3 receptors (IP3Rs) had been excluded because IP3R mutants (itpr) appeared to have normal light responses; however, this was recently challenged by Kohn et al. ("Functional cooperation between the IP3 receptor and...

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Identifiers

PMID: 28660247
DOI: 10.1523/ENEURO.0143-17.2017
PMCID: PMC5483600

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