Article
Disruption of the IP3 receptor gene of Drosophila affects larval metamorphosis and ecdysone release.
Current biology : CB - 1 Jul 1997
Venkatesh K, Hasan G
Abstract excerpt
BACKGROUND: The inositol 1,4,5-trisphosphate (IP3) receptor is an intracellular calcium channel that couples cell membrane receptors, via the second messenger IP3, to calcium signal transduction pathways within many types of cells. IP3 receptor function has been implicated in development, but the...
Topics
- Alleles
- Animals
- Calcium Channels
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Ecdysone
- Ecdysterone
- Inositol 1,4,5-Trisphosphate Receptors
- Larva
- Metamorphosis, Biological
- Mutation
- Receptors, Cytoplasmic and Nuclear
- Transcription Factors
- Transcription, Genetic
