Article
The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors.
Neuron - 1 Apr 1992
Hardie R C, Minke B
Abstract excerpt
Invertebrate phototransduction is an important model system for studying the ubiquitous inositol-lipid signaling system. In the transient receptor potential (trp) mutant, one of the most intensively studied transduction mutants of Drosophila, the light response quickly declines to baseline during prolonged intense light. Using whole-cell recordings from Drosophila photoreceptors, we show that the wild-type...
Topics
- Animals
- Calcium
- Calcium Channels
- Drosophila melanogaster
- Genes
- Ion Channel Gating
- Lanthanum
- Light
- Membrane Potentials
- Phenotype
- Photoreceptor Cells
- Signal Transduction
