Article
Primary cutaneous carcinosarcoma: insights into its clonal origin and mutational pattern expression analysis through next-generation sequencing.
Human pathology - 1 Dec 2013
Paniz Mondolfi Alberto E, Jour George, Johnson Matthew, Reidy Jason, Cason Ronald C, Barkoh Bedia A, Benaim Gustavo, Singh Rajesh, Luthra Rajyalakshmi
Abstract excerpt
Primary cutaneous carcinosarcoma is a rare biphenotypic neoplasm exhibiting both epithelial and sarcomatous elements. Even though its origin and biological aspects remain poorly understood, it has been postulated that this tumor may arise from progenitor cells, which subsequently differentiate into distinct tumor components. We have investigated the histological and immunohistochemical staining patterns of a...
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