Article
Cutaneous basal cell carcinosarcomas: evidence of clonality and recurrent chromosomal losses.
Human pathology - 1 May 2015
Harms Paul W, Fullen Douglas R, Patel Rajiv M, Chang Dannie, Shalin Sara C, Ma Linglei, Wood Benjamin, Beer Trevor W, Siddiqui Javed, Carskadon Shannon, Wang Min, Palanisamy Nallasivam, Fisher Gary J, Andea Aleodor
Abstract excerpt
Cutaneous carcinosarcomas are heterogeneous group of tumors composed of malignant epithelial and mesenchymal components. Although mutation analyses have identified clonal changes between these morphologically disparate components in some subtypes of cutaneous carcinosarcoma, few cases have been analyzed thus far. To our knowledge, copy number variations (CNVs) and copy-neutral loss of heterozygosity (CN-LOH) have...
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