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Article

Identical clonality of both components of mammary carcinosarcoma with differential loss of heterozygosity.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 1997

Zhuang Z, Lininger R A, Man Y G, Albuquerque A, Merino M J, Tavassoli F A

Abstract excerpt

The histogenesis of carcinosarcomas is controversial, specifically with respect to clonality and cell of origin. To answer these questions, tumor cells from both epithelial and spindle-cell components were microdissected from three cases each of mammary carcinosarcoma and its postulated precursor, carcinoma with spindle-cell metaplasia. Clonality was assessed using the principle of X chromosome inactivation. Loss...

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PMID: 9110298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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