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Article

The C. elegans nck-1 gene encodes two isoforms and is required for neuronal guidance.

Developmental biology - 1 Jun 2011

Mohamed Ahmed M, Chin-Sang Ian D

Abstract excerpt

The NCK adaptor proteins are composed entirely of SH3 and SH2 domains and serve as protein interaction bridges for several receptors during signal transduction events. Here we report the molecular and genetic analysis of the Caenorhabditis elegans nck-1 gene. C. elegans nck-1 encodes two isoforms: NCK-1A and a shorter isoform that lacks the first SH3 domain, NCK-1B. C. elegans nck-1 mutants exhibit defects in...

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PMID: 21443870
DOI: 10.1016/j.ydbio.2011.03.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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