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Article

Recognition of classical and heavy chain forms of HLA-B27 by leukocyte receptors.

Current molecular medicine - 1 Feb 2004

Allen Rachel L, Trowsdale John

Abstract excerpt

As an MHC class I protein, the disease association of HLA-B27 with inflammatory arthritis has been widely assumed to imply a role for the T cell antigen receptor (TCR) in disease. However, in addition to their classical antigen-presenting role, HLA class I proteins are recognised by members of the killer immunoglobulin receptor (KIR) and leukocyte immunoglobulin-like receptor (LILR/ILT/LIR) families. Unusual...

Read the complete abstract on PubMed

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Share to Antigen Presentation
Share to beta 2-Microglobulin
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Antigen, T-Cell

Share to Receptors, Immunologic

Share to Receptors, KIR

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Share to Spondylitis, Ankylosing

Source

Identifiers

PMID: 15011960
DOI: 10.2174/1566524043479329

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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