Article
Structure and function of natural killer cell receptors: multiple molecular solutions to self, nonself discrimination.
Annual review of immunology - 1 Jan 2002
Natarajan Kannan, Dimasi Nazzareno, Wang Jian, Mariuzza Roy A, Margulies David H
Abstract excerpt
In contrast to T cell receptors, signal transducing cell surface membrane molecules involved in the regulation of responses by cells of the innate immune system employ structures that are encoded in the genome rather than generated by somatic recombination and that recognize either classical MHC-I molecules or their structural relatives (such as MICA, RAE-1, or H-60). Considerable progress has recently been made...
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