B27 polymorphism and peptide repertoire.

doi:10.1007/BF03342651

Back to search

Article

B27 polymorphism and peptide repertoire.

Clinical rheumatology - 1 Jan 1996

Parham P

Abstract excerpt

Over 130 HLA-B alleles have been defined at the level of nucleotide sequence. Nine of these are subtypes of HLA-B27. To understand how HLA-B27 predisposes towards arthritis it is important to determine which B27 subtypes are associated with disease susceptibility and which are not. A characterist...

Topics

Alleles
Binding Sites
Disease Susceptibility
HLA-B27 Antigen
Humans
Peptides
Polymorphism, Genetic
Sensitivity and Specificity

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.