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Article

Distinct serine residues in CBP and p300 are necessary for their activation by phenylephrine.

The international journal of biochemistry & cell biology - 1 May 2004

Gusterson Rosalind J, Yuan L Wuchao, Latchman David S

Abstract excerpt

The ability of CREB binding protein (CBP) and p300 co-activators to stimulate transcription has previously been shown to be enhanced by treatment of cardiac cells with the hypertrophic agent phenylephrine (PE). This effect is dependent on activation of the mitogen activated protein kinase pathway (p42/44 MAPK). Here, we demonstrate the first identification of potential phosphorylation sites targeted by PE within...

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Identifiers

PMID: 15006641
DOI: 10.1016/j.biocel.2003.10.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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