Article
The transcriptional co-activators CBP and p300 are activated via phenylephrine through the p42/p44 MAPK cascade.
The Journal of biological chemistry - 25 Jan 2002
Gusterson Rosalind, Brar Bhawanjit, Faulkes David, Giordano Antonio, Chrivia John, Latchman David
Abstract excerpt
The CBP and p300 co-activators play a key role in many aspects of gene regulation being recruited to the DNA via transcription factors that are targets for specific signaling pathways. It has previously been demonstrated that in neuronal cells the ability of CBP and p300 to activate transcription...
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