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Article

Drosophila stem-loop binding protein intracellular localization is mediated by phosphorylation and is required for cell cycle-regulated histone mRNA expression.

Molecular biology of the cell - 1 Mar 2004

Lanzotti David J, Kupsco Jeremy M, Yang Xiao-Cui, Dominski Zbigniew, Marzluff William F, Duronio Robert J

Abstract excerpt

Stem-loop binding protein (SLBP) is an essential component of the histone pre-mRNA processing machinery. SLBP protein expression was examined during Drosophila development by using transgenes expressing hemagglutinin (HA) epitope-tagged proteins expressed from the endogenous Slbp promoter. Full-length HA-dSLBP complemented a Slbp null mutation, demonstrating that it was fully functional. dSLBP protein accumulates...

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Share to Cell Cycle
Share to Cell Nucleus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytoplasm

Share to Embryo, Nonmammalian

Share to Histones

Share to RNA-Binding Proteins

Share to RNA Precursors

Share to RNA Processing, Post-Transcriptional

Source

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Identifiers

PMID: 14999087
DOI: 10.1091/mbc.e03-09-0649
PMCID: PMC363087

Genes

SLBP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Drosophila stem-loop binding protein intracellular localization is mediated by phosphorylation and is required for cell cycle-regulated histone mRNA expression.PMID 14999087Read ↗

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