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Article

[MDR (multidrug resistance) in hepatocarcinoma clinical-therapeutic implications].

La Clinica terapeutica - 1 Jan 2000

Petraccia L, Onori P, Sferra R, Lucchetta M C, Liberati G, Grassi M, Gaudio E

Abstract excerpt

Our purpose was to summarize current knowledge on "multidrug resistance", or MDR, an intrinsic or acquired cross resistance to a variety of structurally and functionally unrelated drugs, still representing one of the major problems in the therapy of cancer and other diseases. MDR depends on various mechanisms, the best known being the activity of ABC transport proteins, mainly Pgp, MDR1 gene product,and MRPs; but...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple

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Source

Identifiers

PMID: 14994922

Genes

ABCG2
CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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