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Article

The role of dendritic cells in cancer.

Seminars in immunopathology - 1 Apr 2017

Hansen Morten, Andersen Mads Hald

Abstract excerpt

Though present in low numbers, dendritic cells (DCs) are recognized as major players in the control of cancer by adaptive immunity. The roles of cytotoxic CD8+ T-cells and Th1 helper CD4+ T-cells are well-documented in murine models of cancer and associated with a profound prognostic impact when infiltrating human tumors, but less information is known about how these T-cells gain access to the tumor or how they...

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PMID: 27638181
DOI: 10.1007/s00281-016-0592-y

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