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Article

Genetic association analysis using sibship data: a multilevel model approach.

PloS one - 1 Jan 2012

Zhao Yang, Yu Hao, Zhu Ying, Ter-Minassian Monica, Peng Zhihang, Shen Hongbing, Diao Nancy, Chen Feng

Abstract excerpt

Family based association study (FBAS) has the advantages of controlling for population stratification and testing for linkage and association simultaneously. We propose a retrospective multilevel model (rMLM) approach to analyze sibship data by using genotypic information as the dependent variabl...

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Identifiers

PMID: 22312441
DOI: 10.1371/journal.pone.0031134
PMCID: PMC3270036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22312441-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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