Article
Cytokine gene polymorphisms and the susceptibility to liver cirrhosis in patients with chronic hepatitis C.
Liver international : official journal of the International Association for the Study of the Liver - 1 Dec 2003
Bahr Matthias J, el Menuawy Mohamed, Boeker Klaus H W, Musholt Petra B, Manns Michael P, Lichtinghagen Ralf
Abstract excerpt
BACKGROUND: The speed of fibrosis progression varies considerably between patients with chronic hepatitis C. This study analyzed whether cytokine gene polymorphisms are associated with a progressive course of the disease. METHODS: Leukocyte DNA from 101 patients with chronic hepatitis C, 52 patients with hepatitis C virus (HCV)-induced cirrhosis and 200 Caucasian blood donors was prepared. Using PCR, RFLP and...
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