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Article

Cytokine gene polymorphisms and susceptibility to chronic hepatitis B virus infection in familial clusters from Iran: a cross-sectional study.

BMC infectious diseases - 22 May 2026

Aghcheli Bahman, Behboudi Emad, Naderi Malihe, Hosseini Seyed Masoud, Tatari Mahin, Shahramian Iraj, Khoshnia Masoud, Besharat Sima, Bakhtiari Mehran, Moradi Abdolvahab

Abstract excerpt

BACKGROUND: This study investigated the associations between specific polymorphisms in the Interleukin-10 (IL-10), Interleukin-18 (IL-18), Interleukin-1 beta (IL-1β), and Tumor Necrosis Factor-alpha (TNF-α) cytokine genes and susceptibility to chronic hepatitis B infection (CHB) in Iranian families with a history of the disease. METHODS: This cross-sectional study involved 90 CHB patients, 18 individuals with...

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Identifiers

PMID: 42174460
DOI: 10.1186/s12879-026-13092-1
PMCID: PMC13371698

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