Article
SLC11A1 promoter gene polymorphisms and fibrosis progression in chronic hepatitis C.
Gut - 1 Mar 2004
Romero-Gómez M, Montes-Cano M A, Otero-Fernández M A, Torres B, Sánchez-Muñoz D, Aguilar F, Barroso N, Gómez-Izquierdo L, Castellano-Megias V M, Núñez-Roldán A, Aguilar-Reina J, González-Escribano M F
Abstract excerpt
BACKGROUND AND AIMS: The solute carrier family 11 member 1 (SLC11A1) gene (formerly Nramp1) encodes for the protein solute carrier family 11, member 1. It affects susceptibility and clinical outcome of autoimmune and infectious diseases. We investigated the possible role of the functional polymorphism located in the promoter region of SLC11A1 and tumour necrosis factor (TNF) genes in the progression of fibrosis...
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