Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Blood T-cell receptor chain transcriptome in multiple sclerosis. Characterization of the T cells with altered CDR3 length distribution

26 Feb 2004

Abstract excerpt

Multiple sclerosis is an inflammatory demyelinating disease of the CNS associated with T cells autoreactive for myelin components. In this study, we analysed the T-cell receptor (TCR) usage of the variable beta (Vbeta) chain transcriptome in the blood of multiple sclerosis patients at various stages of the disease using a global and quantitative comparison of the complementarity-determining region 3 length...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunotherapy and Immune Responses
Share to Multiple Sclerosis Research Studies
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14985265
DOI: 10.1093/brain/awh119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Blood T-cell receptor chain transcriptome in multiple sclerosis. Characterization of the T cells with altered CDR3 length distributionPMID 14985265Read ↗

Detailed Characterization of T Cell Receptor Repertoires in Multiple Sclerosis Brain LesionsSemantic proximity Read ↗

Multiple sclerosis: T-cell receptor expression in distinct brain regions.Semantic proximity Read ↗

Risk HLA Variants Affect the T-Cell Repertoire in Multiple SclerosisSemantic proximity Read ↗

Oligoclonal expansion of memory CD8+ T cells in cerebrospinal fluid from multiple sclerosis patientsSemantic proximity Read ↗

T-cell receptor Vbeta gene usage in CSF lymphocytes in X-linked adrenoleukodystrophy.Semantic proximity Read ↗

B Cell Repertoire Diversity and Clonal Expansion in Multiple Sclerosis Brain LesionsSemantic proximity Read ↗

Composition and variation analysis of the TCR β-chain CDR3 repertoire in systemic lupus erythematosus using high-throughput sequencing.Semantic proximity Read ↗

Restricted T-cell receptor V beta gene usage by myelin basic protein-specific T-cell clones in multiple sclerosis: predominant genes vary in individuals.Semantic proximity Read ↗

γδ T cell receptor repertoire in brain lesions of patients with multiple sclerosisSemantic proximity Read ↗

T cell receptor V beta gene usage in the recognition of myelin basic protein by cerebrospinal fluid- and blood-derived T cells from patients with multiple sclerosis.Semantic proximity Read ↗

Comprehensive analysis of the T-cell receptor beta chain gene in rhesus monkey by high throughput sequencingSemantic proximity Read ↗

CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the peripherySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.