Article
T-cell receptor Vbeta gene usage in CSF lymphocytes in X-linked adrenoleukodystrophy.
Journal of molecular recognition : JMR - 1 Jan 2000
Picard Fabienne, Guidoux Sylvie, Martin Thierry, Aubourg Patrick, Pasquali Jean-Louis
Abstract excerpt
X-linked adrenoleukodystrophy (ALD) is a peroxisomal disorder with impaired very-long-chain fatty acid (VLCFA) metabolism that produces a neurological disease with significant variability of clinical phenotypes even within kindred. The two most common forms are the cerebral form (CALD) with an important inflammatory reaction at the active edge of demyelinating lesions, resembling some aspects of multiple...
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